I-Climbazolekunye nePiroctone Olamine zombini zizithako ezisebenzayo ezisetyenziswa kakhulu kwi-shampoo formulations ukulwa ne-dandruff. Nangona zineempawu ezifanayo zokubola kwaye zijolise kwisizathu esifanayo se-dandruff (i-Malassezia fungus), kukho umahluko phakathi kwezi zinto zimbini.
Umahluko omkhulu usekwe kwindlela ezisebenza ngayo.I-ClimbazoleIsebenza ngokuyintloko ngokuthintela i-biosynthesis ye-ergosterol, eyona nto iphambili kwi-membrane yeseli yefungal. Ngokuphazamisa i-membrane yeseli, i-climbazole iyibulala ngempumelelo i-fungus kwaye inciphise i-dandruff. Kwelinye icala, i-Piroctone Olamine isebenza ngokuphazamisa imveliso yamandla ngaphakathi kweeseli ze-fungus, nto leyo ekhokelela ekufeni kwazo. Iphazamisa umsebenzi we-mitochondrial we-fungus, iphazamisa amandla ayo okuvelisa amandla kwaye iphile. Lo mahluko kwindlela yokusebenza ubonisa ukuba zinokuba namanqanaba ahlukeneyo okusebenza ngokuchasene neentlobo ezahlukeneyo zeMalassezia.
Olunye uphawu oluphawulekayo ziimpawu zazo zokunyibilika. I-Climbazole inyibilika ngakumbi kwioyile kunamanzi, nto leyo eyenza ukuba ifaneleke kwiifomyula zeshampoo ezisekelwe kwioyile okanye uhlobo lwe-emulsion. Kwelinye icala, i-Piroctone Olamine inyibilika ngakumbi emanzini, nto leyo evumela ukuba ifakwe lula kwiishampoo ezisekelwe emanzini. Ukukhetha phakathi kwe-climbazole kunye ne-Piroctone Olamine kunokuxhomekeka kwifomyula efunwayo kunye nezinto ezikhethwa ngumvelisi.
Ngokuphathelele ukhuseleko, zombini i-climbazole kunye ne-Piroctone Olamine zinembali entle kwaye azinazo iziphumo ebezingalindelekanga ezininzi. Zithathwa njengezikhuselekileyo ekusetyenzisweni ngaphandle kwesikhumba, nangona kukho ukuvakalelwa komntu ngamnye okanye i-allergies. Kucetyiswa rhoqo ukuba ulandele imiyalelo kwaye udibane neengcali zempilo ukuba kukho naziphi na iziphumo ezibi.
Iifomyula ze-shampoo zihlala zidibanai-climbazoleokanye iPiroctone Olamine kunye nezinye izithako ezisebenzayo ukuphucula ukusebenza kwazo ngokuchasene ne-dandruff. Umzekelo, zinokudityaniswa ne-zinc pyrithione, i-selenium sulfide, okanye i-salicylic acid ukubonelela ngendlela ebanzi yokulawula i-dandruff.
Ngamafutshane, nangona zombini i-climbazole kunye ne-Piroctone Olamine zizinto ezisebenzayo zokubola ezisetyenziswa kwi-shampoo formulations, zahlukile kwindlela yazo yokusebenza kunye neempawu zokunyibilika. Ukukhetha phakathi kwezi zimbini kunokuxhomekeka kukhetho lwe-formulation kunye neempawu ezifunwayo ze-shampoo product.
Ixesha lokuthumela: Juni-13-2023