I-Cinnamaldehyde ibandakanya i-85% ukuya kwi-90% yeoyile ebalulekileyo yesinamoni, kwaye iTshayina yenye yezona ndawo ziphambili zokutyala isinamoni, kwaye izixhobo ze-cinnamaldehyde zityebile. Ulwakhiwo lwemolekyuli ye-Cinnamaldehyde (C9H8O) liqela le-phenyl eliqhagamshelwe kwi-acrylein, kwimeko yendalo yolwelo olutyheli okanye olutyheli olumdaka olunencasa yesinamoni kunye ne-coke, olunokusetyenziswa kwiziqholo kunye nezinongo. Okwangoku, kubekho iingxelo ezininzi malunga nesenzo se-cinnamaldehyde sokulwa neentsholongwane esibanzi kunye nendlela esebenza ngayo, kwaye izifundo zibonise ukuba i-cinnamaldehyde inefuthe elihle lokulwa neentsholongwane kwiibhaktheriya kunye neefungi. Kwicandelo lezonyango, ezinye izifundo zihlolisise inkqubela yophando lwe-cinnamaldehyde kwizifo ze-metabolic, izifo zenkqubo yokujikeleza kwegazi, ukulwa nethumba kunye nezinye izinto, kwaye zifumanise ukuba i-cinnamaldehyde inefuthe elihle lokulwa nesifo seswekile, ukulwa nokutyeba, ukulwa nethumba kunye neminye imisebenzi yezonyango. Ngenxa yemithombo yayo etyebileyo, izithako zendalo, ukhuseleko, ubuthi obuphantsi, incasa eyahlukileyo kunye nefuthe le-antibacterial elibanzi, sisongezelelo sokutya esivunyiweyo yi-United States Food and Drug Administration kunye ne-China. Nangona isixa esiphezulu singakhawulelwanga ekusetyenzisweni, ukuguquguquka kwayo kunye nevumba elibi kuyayithintela ukusetyenziswa kwayo ngokubanzi ekutyeni. Ukulungisa i-cinnamaldehyde kwifilimu yokupakisha ukutya kunokuphucula ukusebenza kwayo okulwa neentsholongwane kunye nokunciphisa impembelelo yayo yokuziva ekutyeni, kwaye kudlala indima ekuphuculeni umgangatho wokugcina ukutya kunye nokuthuthwa kunye nokwandisa ubomi beshelufu.
1. I-matrix ye-membrane edibeneyo ye-antibacterial
Uninzi lophando malunga nefilimu yokupakishwa kwe-antibacterial yokutya lusebenzisa izinto zendalo nezibolayo njenge-matrix yokwenza ifilimu, kwaye ifilimu yokupakishwa ilungiswa ngendlela yokugquma, ukuphosa okanye indlela yokukhupha ubushushu obuphezulu. Ngenxa yendlela eyahlukileyo yokusebenza kunye nokuhambelana phakathi kwe-substrates ezahlukeneyo ze-membrane kunye nezinto ezisebenzayo, iimpawu ze-membrane egqityiweyo zahlukile, ngoko ke kubaluleke kakhulu ukukhetha i-substrate efanelekileyo ye-membrane. Ii-substrates ezisetyenziswa rhoqo zokwenza ifilimu ziquka izinto ezibolayo zokwenziwa ezifana ne-polyvinyl alcohol kunye ne-polypropylene, izinto zendalo ezifana ne-polysaccharides kunye neeproteni, kunye nezinto ezidibeneyo. I-Polyvinyl alcohol (PVA) yi-polymer ethe tyaba, edla ngokwenza isakhiwo senethiwekhi esinemilinganiselo emithathu xa idityanisiwe, kwaye ineempawu ezintle zoomatshini kunye neempawu zokuthintela. Izixhobo ze-matrix ezifana ne-membrane yendalo zininzi kwaye zifumaneka kakhulu. Umzekelo, i-polylactic acid inokuvundiswa kwizinto ezikrwada ezifana nesitatshi kunye nombona, enemithombo eyaneleyo nevuselelekayo, i-biodegradability elungileyo kunye ne-biocompatibility, kwaye iyinto efanelekileyo yokupakisha enobuhlobo nokusingqongileyo. I-composite matrix idla ngokwenziwa zii-membrane matrices ezimbini okanye ngaphezulu, ezinokudlala indima ehambelanayo xa kuthelekiswa ne-membrane matrix enye.
Iimpawu zoomatshini kunye neempawu zomqobo zizibonakaliso ezibalulekileyo zokuvavanya ukufaneleka kwefilimu yokupakisha. Ukongezwa kwe-cinnamaldehyde kuya kudityaniswa ne-polymer membrane matrix kwaye ngaloo ndlela kunciphise ukugeleza kwemolekyuli, ukuncipha kobude xa kuqhekeka kungenxa yokungaqhubeki kwesakhiwo senethiwekhi ye-polysaccharide, kwaye ukwanda kwamandla okutsalwa kubangelwa kukwanda kweqela le-hydrophilic ngexesha lenkqubo yokwenza ifilimu ebangelwa kukongeza i-cinnamaldehyde. Ukongeza, ukuvunyelwa kwegesi kwe-cinnamaldehyde composite membrane ngokubanzi kwandisiwe, okunokubangelwa kukusasazwa kwe-cinnamaldehyde kwi-polymer ukwenza ii-pores, ii-voids kunye neetshaneli, ukunciphisa ukumelana nokudluliselwa kobuninzi beemolekyuli zamanzi, kwaye ekugqibeleni kukhokelele ekwandeni kokuvunyelwa kwegesi kwe-cinnamaldehyde composite membrane. Iimpawu zoomatshini kunye nokuvunyelwa kwee-membrane ezininzi ezidibeneyo ziyafana, kodwa ulwakhiwo kunye neempawu ze-substrates ezahlukeneyo ze-polymer zahlukile, kwaye ukusebenzisana okwahlukileyo ne-cinnamaldehyde kuya kuchaphazela ukusebenza kwefilimu yokupakisha, kwaye emva koko kuchaphazele ukusetyenziswa kwayo, ngoko ke kubaluleke kakhulu ukukhetha i-substrate ye-polymer efanelekileyo kunye noxinzelelo.
Okwesibini, indlela yokubopha ifilimu ye-cinnamaldehyde kunye ne-packaging
Nangona kunjalo, i-cinnamaldehyde inyibilika kancinci emanzini kwaye inokunyibilika kwe-1.4 mg/mL kuphela. Nangona iteknoloji yokuxuba ilula kwaye ilula, amanqanaba amabini e-cinnamaldehyde enyibilikayo ngamafutha kunye ne-membrane-soluble matrix yamanzi azizinzanga, kwaye iimeko zobushushu obuphezulu kunye noxinzelelo oluphezulu ezifunekayo kwinkqubo yokwenza ifilimu zinciphisa kakhulu uxinzelelo lwe-cinnamaldehyde ekhoyo kwi-membrane. Kunzima ukufezekisa isiphumo esifanelekileyo se-bacteriostatic. Iteknoloji yokufakela yinkqubo yokusebenzisa izinto zodonga ukusonga okanye ukufunxa into esebenzayo ekufuneka ifakwe ukuze inike inkxaso yokusebenza okanye ukhuseleko lweekhemikhali. Ukusetyenziswa kweteknoloji yokufakela ukulungisa i-cinnamaldehyde kwizinto zokupakisha kunokwenza ukukhululwa kwayo kancinci, kuphucule izinga lokugcina, kwandise ukuguga kwe-antibacterial yefilimu, kwaye kuphucule iipropati zoomatshini zefilimu yokupakisha. Okwangoku, iindlela eziqhelekileyo zokwakha i-cinnamaldehyde zokudibanisa i-cinnamaldehyde kunye nefilimu yokupakisha zinokwahlulwa zibe ngamacandelo amabini: ukwakhiwa kwe-carrier yokwenziwa kunye nokwakhiwa kwe-carrier yendalo, kubandakanya ukufakwa kwe-polymer, ukufakwa kwe-nano liposome, ukufakwa kwe-cyclodextrin, ukubopha kwe-nano clay okanye ukulayisha. Ngokudibanisa ukuhlanganiswa kweeleya kunye nokujikeleza nge-electro, isithwali sokuhambisa i-cinnamaldehyde sinokwenziwa ngcono, kwaye indlela yokusebenza kunye noluhlu lwesicelo se-cinnamaldehyde lunokuphuculwa.
Ukusetyenziswa kwefilimu yokupakisha ukutya esebenzayo yesinamoni e-aldehyde
Iintlobo ezahlukeneyo zokutya zinomthamo wamanzi owahlukileyo, ukwakheka kwezondlo kunye neemeko zokugcina nezokuthutha, kwaye indlela yokukhula kwezinto ezincinci ezibolayo yahlukile kakhulu. Isiphumo sokugcinwa kwe-cinnamaldehyde antibacterial packaging yokutya okwahlukeneyo nayo yahlukile.
1. Impembelelo yokugcina imifuno neziqhamo zintsha
I-China ityebile kwimithombo yendalo, apho imveliso kunye nokusetyenziswa kwemifuno neziqhamo kwimarike kukhulu. Nangona kunjalo, umswakama kunye nomthamo weswekile kwimifuno neziqhamo uphezulu, utyebile kwisondlo, kwaye usengozini yokungcola kweentsholongwane kunye nokuwohloka ngexesha lokugcina, ukuthutha kunye nokuthengisa. Okwangoku, ukusetyenziswa kwefilimu yokupakisha elwa namagciwane yindlela ebalulekileyo yokuphucula umgangatho wokugcina kunye nokuthutha imifuno neziqhamo kunye nokwandisa ubomi bazo eshelufini. Ukupakisha ifilimu edibeneyo ye-cinnamaldehyde-polylactic acid yama-apile kunokunciphisa ukulahleka kwezondlo, kuthintele ukukhula kwe-rhizopus, kwaye kwandise ixesha lokugcina lama-apile ukuya kwiintsuku ezili-16. Xa ifilimu yokupakisha ukutya esebenzayo ye-cinnamaldehyde isetyenziswa kwiphakheji yekaroti esandul’ ukusikwa, ukukhula kwesikhunta kunye nemvubelo kwathintelwa, izinga lokubola kwemifuno lancitshiswa, kwaye ubomi beshelufini bandiswa ukuya kwi-12d.
2. Isiphumo sokugcina inyama icocekile Ukutya kwenyama kutyebile kwiproteni, amafutha kunye nezinye izinto, kutyebile kwisondlo kunye nencasa eyahlukileyo. Kwiqondo lobushushu begumbi, ukuzala kweentsholongwane kubangela ukubola kweeproteni zenyama, iicarbohydrate kunye namafutha, okubangela ukonakala kwenyama, umphezulu onamathelayo, umbala omnyama, ukulahleka kokuqina, kunye nevumba elibi. Ifilimu yokupakisha ukutya esebenzayo yeCinnamaldehyde isetyenziswa kakhulu kwiphakheji yehagu kunye neentlanzi, ikakhulu ithintela ukukhula kweStaphylococcus aureus, i-Escherichia coli, i-aeromonas, i-yeast, iibhaktheriya ze-lactic acid kunye nezinye iibhaktheriya, kwaye inokwandisa ubomi beshelufu ukusuka kwi-8 ~ 14d.
3. Impembelelo yokugcina iimveliso zobisi zintsha Okwangoku, ukusetyenziswa kweemveliso zobisi eTshayina kuyanda minyaka le. Itshizi yimveliso yobisi ebilisiweyo enexabiso lesondlo kunye neproteni etyebileyo. Kodwa itshizi inobomi obufutshane bokuhlalisa, kwaye izinga lenkunkuma kumaqondo obushushu aphantsi lisaxhalabisa. Ukusetyenziswa kwefilimu yokupakisha ukutya ye-cinnamic aldehyde kunokwandisa ubomi beshelufu yetshizi, kuqinisekise incasa entle yetshizi, kwaye kuthintele ukuwohloka kwetshizi. Kwizilayi zetshizi kunye neesosi zetshizi, ubomi beshelufu buyandiswa ukuya kwiintsuku ezingama-45 kunye neentsuku ezingama-26 ngokulandelelana emva kokusebenzisa ukupakisha okusebenzayo kwe-cinnamaldehyde, okunceda ukonga izixhobo.
4. Isiphumo sokugcina ukutya okutsha kwesitatshi sisonka kunye nekhekhe ziimveliso zesitatshi, ezenziwe ngomgubo wengqolowa, umqhaphu wepayini othambileyo, omnandi kwaye umnandi. Nangona kunjalo, isonka kunye nekhekhe zihlala ixesha elifutshane kwaye zisengozini yokungcoliswa ngumngundo ngexesha lokuthengisa, nto leyo ebangela ukuwohloka komgangatho kunye nokuchithwa kokutya. Ukusetyenziswa kwe-cinnamaldehyde ekupakishweni kokutya okusebenzayo kwikhekhe lesiponji kunye nesonka esisikiweyo kunokuthintela ukukhula kunye nokwanda kwe-penicillium kunye nomngundo omnyama, kwaye kwandise ubomi beshelufu ukuya kwi-10 ~ 27d, ngokulandelelana.
I-Cinnamaldehyde ineengenelo zokuba ininzi kakhulu, ine-bacteriostasis ephezulu kwaye inetyhefu ephantsi. Njenge-arhente ye-bacteriostasis ekupakisheni ukutya okusebenzayo, ukuzinza kunye nokukhululwa kancinci kwe-cinnamaldehyde kunokuphuculwa ngokwakha nokwenza ngcono isithwali sokuhambisa, nto leyo ibaluleke kakhulu ekuphuculeni umgangatho wokugcina kunye nokuthutha ukutya okutsha kunye nokwandisa ubomi bokutya obuhlala ixesha elide. Kwiminyaka yakutshanje, i-cinnamaldehyde yenze impumelelo eninzi kunye nenkqubela phambili kuphando lokugcinwa kokupakisha ukutya, kodwa uphando oluhambelanayo lwesicelo lusekwinqanaba lokuqala, kwaye kusekho iingxaki ekufuneka zisonjululwe. Ngophando oluthelekisayo lwemiphumo yeziphathali ezahlukeneyo zokuhambisa kwiipropati zoomatshini kunye neepropati zomqobo we-membrane, uphando olunzulu lwendlela yokusebenza kwe-cinnamaldehyde kunye nesithwali kunye ne-kinetics yayo yokukhululwa kwiindawo ezahlukeneyo, uphando lwempembelelo yomthetho wokukhula kweentsholongwane ekutyeni ekonakalisweni kokutya, kunye nendlela yokulawula ukupakisha ii-antibacterial kwisantya kunye nexesha lokukhululwa kwee-antimicrobial agents. Yila kwaye uphuhlise iinkqubo zokupakisha ezisebenzayo ezinokuhlangabezana neemfuno ezahlukeneyo zokugcinwa kokutya.
Ixesha leposi: Jan-03-2024