Hydroxyacetophenone

I-P-hydroxyacetophenone sisithako sokhathalelo lwesikhumba esisebenza ngeendlela ezininzi, ikakhulu sinemisebenzi yokwenza mhlophe kwaye ihombise ibala, i-anti-bacterial and anti-inflammatory, kunye nokuthomalalisa kunye nokuthomalalisa. Inokuthintela ukuhlanganiswa kwe-melanin kunye nokunciphisa i-pigmentation kunye ne-freckles. Njenge-antibacterial agent ebanzi, inokuphucula usulelo lwesikhumba. Iyakwazi ukuthomalalisa ukucaphuka kwesikhumba kwaye ilungele ulusu olubuthathaka.

1. Ukukhuthaza ukukhutshwa kwenyongo

Inomphumela we-cholagogic, inokukhuthaza ukukhutshwa kwe-bile, inceda ukukhupha i-bilirubin kunye ne-bile acids kwi-bile, kwaye inefuthe elithile elincedisayo kunyango lwe-jaundice kunye nezinye izifo zesibindi kunye ne-gallbladder. Ikwasetyenziswa ekulungiseleleni amachiza athile, anje ngeziyobisi ze-choleretic kunye nezinye iziyobisi ze-organic synthetic, njengento ephakathi kwi-synthesis yeziyobisi.

2. Iimpawu ze-Antioxidant

Ngenxa yokuba iqukethe amaqela e-phenolic hydroxyl,p-hydroxyacetophenoneineempawu ezithile ze-antioxidant kwaye idla ngokusetyenziswa njenge-antioxidant. I-antioxidant kunye ne-antibacterial properties zombini zivela kumaqela e-hydroxyl, okwenza i-antioxidant (i-phenolic kunye neempawu ze-ketone). Inezixhobo ezinamandla zokulwa ne-antioxidant, inokuphelisa i-radicals yamahhala emzimbeni, ikhusela iiseli kumonakalo we-oxidative, kwaye ngoko inemisebenzi yokuthintela izifo kunye nokuchasana nokuguga.

3. I-Antibacterial kunye ne-anti-inflammatory

Isebenza ngokuchasene nokungunda, inamandla okubulala eAspergillus Niger, kwaye inefuthe elithile lokuthintela kwiPseudomonas aeruginosa. Inozinzo olubalaseleyo phakathi koluhlu olubanzi lwe-pH kunye nobushushu. Inempembelelo ethile yonyango oluncedisayo kwizifo zesikhumba kunye nokuvutha.

4. Njengesiqholo kunye nesilondolozi

Ikwasetyenziswa rhoqo njengesixhasi solondolozo (esihlala sidityaniswa ne-hexanediol, i-pentyl glycol, i-octanol, i-ethylhexylglycerol, njl. njl. ukuze kuthathelwe indawo izithinteli zemveli).I-P-hydroxyacetophenoneisetyenziswa ngokuqhelekileyo njengesiqholo kunye nesigcinakaliso, esinokwandisa ixesha leshelufu yeemveliso kwaye izinike amavumba athile.

5. I-arhente emhlophe

Ukusuka kwi "preservative" ukuya kwi "whitening agent", ukufunyanwa kwep-hydroxyacetophenoneusibonisile ukuba ezinye iimathiriyeli ekrwada kwizinto zokuthambisa zisenokuthi zibambe amandla amaninzi angekasetyenziswa.

Inxalenye carbonyl yep-hydroxyacetophenoneinokungena ngokunzulu kwindawo esebenzayo ye-tyrosinase, ngelixa iqela layo le-phenolic hydroxyl linokwenza izibophelelo ze-hydrogen ezizinzile kunye neentsalela eziphambili ze-amino acid. Le ndlela ekhethekileyo yokubopha yenza ukuba "itshixe" ngokuqinileyo i-tyrosinase, ngaloo ndlela ivalela ukuveliswa kwe-melanin.

Kwixesha elizayo, ngokunzulu kophando oluninzi kunye nokuqokelela kokuqinisekiswa kweklinikhi,p-hydroxyacetophenonekulindeleke ukuba idlale indima ebaluleke kakhulu kwintsimi yokwenziwa mhlophe kunye nokunakekelwa kwesikhumba, ibe sisizukulwana esilandelayo sokwenza izinto ezimhlophe ezidibanisa ukhuseleko kunye nokusebenza okubalulekileyo.