α-arbutinkunye ne-β-arbutin zikhompawundi ezimbini ezisondeleleneyo zeekhemikhali ezihlala zisetyenziswa kwiimveliso zokhathalelo lwesikhumba ngenxa yokukhanya kolusu kunye neziphumo ezikhanyayo.Ngelixa babelana ngesakhiwo esisisiseko esifanayo kunye nendlela yokwenza, kukho ukungafani okufihlakeleyo phakathi kwezi zibini ezinokuchaphazela ukusebenza kwazo kunye nemiphumo enokubakho.
Ngokwesakhiwo, zombini i-α-arbutin kunye ne-β-arbutin zii-glycosides ze-hydroquinone, okuthetha ukuba bane-molecule yeglucose edityaniswe kwi-molecule ye-hydroquinone.Oku kufana kwesakhiwo kuvumela zombini iikhompawundi ukuba zithintele i-enzyme tyrosinase, ebandakanyeka kwimveliso ye-melanin.Ngokunqanda i-tyrosinase, ezi zixhobo zinokunceda ukunciphisa ukuveliswa kwe-melanin, okukhokelela ekukhanyeni kunye nethoni yesikhumba.
Umahluko ophambili phakathi kwe-α-arbutin kunye ne-β-arbutin ilele kwindawo yebhondi ye-glycosidic phakathi kweglucose kunye ne-hydroquinone moieties:
I-α-arbutin: Kwi-α-arbutin, ibhondi ye-glycosidic iqhotyoshelwe kwindawo ye-alpha yeringi ye-hydroquinone.Oku kubekwa kukholelwa ukuba konyusa uzinzo kunye nokunyibilika kwe-α-arbutin, iyenza isebenze ngakumbi kwisicelo solusu.Ibhondi ye-glycosidic iphinda inciphise amandla okuba ne-oxidation ye-hydroquinone, enokuthi ikhokelele ekubunjweni kweekhompawundi ezimnyama ezichasene nesiphumo esifunwayo sokukhanya kwesikhumba.
I-β-arbutin: Kwi-β-arbutin, ibhondi ye-glycosidic iqhotyoshelwe kwindawo ye-beta yeringi ye-hydroquinone.Ngelixa i-β-arbutin iphinda isebenze ekuthinteleni i-tyrosinase, ingazinza kakhulu kune-α-arbutin kwaye ithandeke ngakumbi kwi-oxidation.Le oxidation inokubangela ukwakheka kweekhompawundi ezimdaka ezinganqweneleki kangako ekukhanyiseni ulusu.
Ngenxa yozinzo olukhulu kunye nokunyibilika kwayo, i-α-arbutin ihlala ithathwa njengeyona ndlela isebenzayo kwaye ikhethwayo kwizicelo zokhathalelo lwesikhumba.Kukholelwa ukuba inika iziphumo ezingcono zokukhanya kolusu kwaye ayifane ibangele ukujika kombala okanye iziphumo ebezingalindelekanga ezingafunekiyo.
Xa kuqwalaselwa iimveliso zesikhumba eziqulathearbutin, kubalulekile ukufunda ileyibhile yesithako ukufumanisa ukuba i-α-arbutin okanye i-β-arbutin iyasetyenziswa.Ngelixa zombini iikhompawundi zinokusebenza, i-α-arbutin ngokuqhelekileyo ithathwa njengokhetho oluphezulu ngenxa yokuzinza kwayo kunye namandla.
Kukwabalulekile ukuqaphela ukuba ubuthathaka bolusu lomntu ngamnye bunokwahluka.Abanye abantu banokufumana iziphumo ebezingalindelekanga ezinjengokucaphuka kwesikhumba okanye ububomvu xa usebenzisa iimveliso ezine-arbutin.Njengaso nasiphi na isithako se-skincare, kuyacetyiswa ukuba wenze uvavanyo lwe-patch phambi kokufaka imveliso kwindawo enkulu yesikhumba kwaye udibane ne-dermatologist ukuba unayo nayiphi na inkxalabo malunga nokuphendula okunokwenzeka.
Ukuqukumbela, zombini i-α-arbutin kunye ne-β-arbutin zii-glycosides ze-hydroquinone ezisetyenziselwa ukukhanyisa ulusu.Nangona kunjalo, indawo ye-α-arbutin yebhondi ye-glycosidic kwindawo ye-alpha inika uzinzo olukhulu kunye nokunyibilika, iyenza ibe lolona khetho luthandwayo kwiimveliso ze-skincare ezijolise ekunciphiseni i-hyperpigmentation kunye nokufezekisa ithoni yolusu ngakumbi.
Ixesha lokuposa: Aug-30-2023