I-Formaldehyde kunye ne-glutaraldehydezombini ezi khemikhali zisetyenziswa njengeearhente zokudibanisa kwiindlela ezahlukeneyo zokusebenza, ingakumbi kwicandelo lebhayoloji, ikhemistri, kunye nesayensi yezinto. Nangona zisebenza ngeenjongo ezifanayo ekudibaniseni ii-biomolecules kunye nokugcina iisampulu zebhayoloji, zineempawu ezahlukeneyo zeekhemikhali, ukusabela, ubuthi, kunye nokusetyenziswa.
Ukufana:
Ii-Crosslinking Agents: Zombini i-formaldehyde kunyei-glutaraldehyde zi-aldehydes, oko kuthetha ukuba baneqela le-carbonyl (-CHO) ekupheleni kwesakhiwo sabo seemolekyuli. Umsebenzi wabo oyintloko kukwenza ii-covalent bonds phakathi kwamaqela asebenzayo ee-biomolecules, nto leyo ebangela ukudibana. Ukudibana kubalulekile ekuzinziseni isakhiwo seesampuli zebhayoloji, ukuzenza zibe namandla ngakumbi kwaye zimelane nokuwohloka.
Ukusetyenziswa kwe-Biomedical: Zombini i-formaldehyde kunye ne-glutaraldehyde zisetyenziswa kakhulu kwicandelo le-biomedical. Zisetyenziswa kakhulu ekuqiniseni nasekulondolozeni izicubu kwizifundo ze-histology kunye ne-pathology. Izicubu ezidityanisiweyo zigcina ulungelelwaniso lwazo lwesakhiwo kwaye zinokusetyenzwa ngakumbi ngeenjongo ezahlukeneyo zohlalutyo kunye nokuxilongwa.
Ulawulo lweeMicrobial: Zombini ezi arhente zineempawu zokulwa neentsholongwane, nto leyo ezenza zibe luncedo kwiinkqubo zokubulala iintsholongwane kunye nokubulala iintsholongwane. Zingavala iintsholongwane, iintsholongwane kunye nefungi, zinciphisa umngcipheko wokungcola kwiindawo zelebhu nakwizixhobo zonyango.
Izicelo zemizi-mveliso: Zombini i-formaldehyde kunyei-glutaraldehydeZisetyenziswa kwizicelo ezahlukeneyo zoshishino. Zisetyenziswa ekuveliseni izinto zokuncamathelisa, iiresini, kunye neepolymers, kunye nakwimizi-mveliso yesikhumba neyelaphu.
Umahluko:
Ulwakhiwo lweeKhemikhali: Umahluko ophambili phakathi kwe-formaldehyde kunye ne-glutaraldehyde ukwizakhiwo zazo zemolekyuli. I-Formaldehyde (CH2O) yeyona aldehyde ilula, eyenziwe yi-atom enye yekhabhoni, ii-atom ezimbini ze-hydrogen, kunye ne-atom enye yeoksijini. I-Glutaraldehyde (C5H8O2), kwelinye icala, yi-aldehyde ye-aliphatic eyinkimbinkimbi ngakumbi, equlathe ii-atom ezintlanu zekhabhoni, ii-atom ezisibhozo ze-hydrogen, kunye nee-atom ezimbini zeoksijini.
Ukusabela: I-Glutaraldehyde idla ngokuba negalelo elingakumbi kune-formaldehyde ngenxa yekhonkco layo elide lekhabhoni. Ukubakho kweeathom ezintlanu zekhabhoni kwi-glutaraldehyde kuyivumela ukuba ikwazi ukuhlanganisa imigama emide phakathi kwamaqela asebenzayo kwii-biomolecules, nto leyo ekhokelela ekudibaneni ngokukhawuleza nangokusebenzayo.
Ukusebenza kakuhle kokudibanisa: Ngenxa yokusabela kwayo okuphezulu, i-glutaraldehyde idla ngokusebenza ngakumbi ekudibaniseni ii-biomolecule ezinkulu, ezifana neeproteni kunye nee-enzymes. I-Formaldehyde, nangona isakwazi ukudibanisa, inokufuna ixesha elingakumbi okanye ugxininiso oluphezulu ukuze kufezekiswe iziphumo ezifanayo ngee-molecule ezinkulu.
Ubuthi: I-Glutaraldehyde yaziwa ngokuba yityhefu ngaphezu kwe-formaldehyde. Ukuvezwa ixesha elide okanye okukhulu kwi-glutaraldehyde kunokubangela ukurhawuzelelwa lusu kunye nokuphefumla, kwaye kuthathwa njengento evuselela imvakalelo, oko kuthetha ukuba inokukhokelela kwiimpendulo ze-allergy kwabanye abantu. Ngokwahlukileyo koko, i-formaldehyde yaziwa kakhulu ngokuba yi-carcinogen kwaye ibeka emngciphekweni impilo, ngakumbi xa iphefumlelwa okanye idibana nolusu.
Ukusetyenziswa: Nangona zombini ezi khemikhali zisetyenziswa ekuqiniseni izicubu, zihlala zikhethwa ngeenjongo ezahlukeneyo. I-Formaldehyde isetyenziswa rhoqo kwizicelo ze-histological kunye ne-embalming, ngelixa i-glutaraldehyde ifanelekile ngakumbi ekugcineni izakhiwo zeseli kunye neendawo ze-antigenic kwi-electron microscopy kunye nezifundo ze-immunohistochemical.
Uzinzo: I-Formaldehyde itshintshatshintsha kakhulu kwaye idla ngokuphuma ngokukhawuleza kune-glutaraldehyde. Le mpawu inokuchaphazela iimfuno zokuphathwa kunye nokugcinwa kwee-agents ezidibanisayo.
Ngamafutshane, i-formaldehyde kunye ne-glutaraldehyde zabelana ngeempawu ezifanayo njengee-agents ezidibanisa izinto, kodwa zahlukile kakhulu kwizakhiwo zazo zeekhemikhali, ukusabela kwazo, ubuthi, kunye nokusetyenziswa kwazo. Ukuqonda okufanelekileyo kwezi mahluko kubalulekile ekukhetheni i-agent efanelekileyo yokudibanisa izinto ngeenjongo ezithile kunye nokuqinisekisa ukusetyenziswa okukhuselekileyo nokusebenzayo kwiimeko ezahlukeneyo zesayensi, zonyango, kunye nezoshishino.
Ixesha lokuthumela: Julayi-28-2023