Apha ngezantsi kukho intshayelelo emfutshane malunga neendlela zokusebenza, iintlobo kunye novavanyo oluchazwe kwiindlela ezahlukeneyo zokugcina izinto ezigciniweyo
1.Indlela iyonke yokusebenzaizithinteli
Izithinteli zezona zinto zisetyenziswa kakhulu ziikhemikhali ezinceda ekubulaleni okanye ekuthinteleni imisebenzi yeentsholongwane kwizinto zokuthambisa, kunye nokugcina umgangatho wezinto zokuthambisa ixesha elide.
Nangona kunjalo, kufuneka kuqatshelwe ukuba izithinteli aziyonto yokulwa neentsholongwane kuba azinawo amandla okulwa neentsholongwane, kwaye zisebenza kuphela xa zisetyenziswa ngobuninzi obaneleyo okanye xa zidibene ngqo neentsholongwane.
Izithinteli zithintela ukukhula kweentsholongwane, zithintela ukwenziwa kwee-enzymes ezibalulekileyo zemetabolism, zikwathintela ukwenziwa kweeproteni kwiinxalenye ezibalulekileyo zeseli okanye ukwenziwa kwe-nucleic acid.
2.Izinto ezichaphazela imisebenzi yeZigcini
Zininzi izinto ezinegalelo kwimpembelelo yezigcina-zimonyo. Ziquka;
a.Isiphumo se-pH
Utshintsho kwi-pH lunegalelo ekuqhekekeni kwezigcini ze-organic acid, kwaye ke luchaphazela ukusebenza kakuhle kwezigcini. Umzekelo, kwi-pH 4 kunye ne-pH 6, i-2-bromo-2-nitro-1,3-propanediol izinzile kakhulu.
b.Iziphumo zejeli kunye namasuntswana aqinileyo
I-Koalin, i-magnesium silicate, i-aluminium njl.njl., ziinxalenye zepowder ezikhoyo kwezinye izinto zokuthambisa, ezidla ngokufunxa isithinteli-zintsholongwane kwaye ngaloo ndlela zikhokelela ekulahlekelweni ngumsebenzi yi-preservative. Nangona kunjalo, ezinye ziyasebenza ekufunxeni iintsholongwane ezikhoyo kwi-preservative. Kwakhona, ukudityaniswa kwejeli ye-polymer enyibilikayo emanzini kunye nesithinteli-zintsholongwane kunceda ekunciphiseni ukuxinana kwesithinteli-zintsholongwane kwi-cosmetics, kwaye oku kunciphise nefuthe lesithinteli-zintsholongwane.
c.Isiphumo sokunyibilika kwe-surfactants ezingezizo i-ionic
Ukunyibilika kwee-surfactants ezahlukeneyo ezifana nee-surfactants ezingezizo ii-ionic kwii-preservatives nako kuchaphazela umsebenzi ngokubanzi wee-preservatives. Nangona kunjalo, ii-surfactants ezingezizo ii-ionic ezinyibilikayo kwioyile ezifana ne-HLB=3-6 zaziwa ngokuba nokukwazi ukucima ukusebenza okuphezulu kwii-preservatives xa kuthelekiswa nee-surfactants ezinyibilikayo emanzini ezingezizo ii-ionic ezinexabiso eliphezulu le-HLB.
d.Isiphumo sokonakala kwezinto zokugcina izinto ezigcina izinto zicocekile
Kukho ezinye izinto ezifana nokufudumeza, ukukhanya njl.njl., ezibangela ukuwohloka kwezigcini, ngaloo ndlela zibangela ukuncipha kwesiphumo sazo sokubulala iintsholongwane. Ngaphezu koko, ezinye zezi ziphumo zikhokelela kwimpendulo ye-biochemical ngenxa yokubulala iintsholongwane ngemitha kunye nokubulala iintsholongwane.
e.Eminye imisebenzi
Ngokufanayo, ezinye izinto ezinje ngokubakho kweencasa kunye nee-chelating agents kunye nokusasazeka kwezigcini kwi-oyile-water-phase ezimbini nazo ziya kuncedisa ekunciphiseni umsebenzi wezigcini ukuya kuthi ga kwinqanaba elithile.
3.Iimpawu ze-antiseptic ze-preservatives
Iimpawu zokubulala iintsholongwane zezithako zokugcina iintsholongwane zifanelekile ukuqwalaselwa. Ukuba nezithako zokugcina iintsholongwane ezininzi kwizithako zokuthambisa ngokuqinisekileyo kuya kuyenza ikruquke, ngelixa ukunqongophala koxinzelelo kuya kuyichaphazela i-antiseptic.iipropati zezigciniEyona ndlela ilungileyo yokuvavanya oku kukusebenzisa uvavanyo lwebhayoloji olubandakanya uxinzelelo oluncinci lokuthintela (i-MIC) kunye novavanyo lwendawo yokuthintela.
Uvavanyo lwesangqa se-Bacteriostatic: Olu vavanyo lusetyenziselwa ukufumanisa ezo bhaktheriya kunye nomngundo onamandla okukhula ngokukhawuleza emva kokulima kwindawo efanelekileyo. Kwimeko apho idiski yephepha lesihluzo elifakwe isigcini ilahlwa embindini wepleyiti ye-culture medium, kuya kubakho isangqa se-bacteriostatic esakhiwe ngeenxa zonke ngenxa yokungena kwesigcini. Xa kulinganiswa ububanzi besangqa se-bacteriostatic, singasetyenziswa njengomlinganiselo wokulinganisa ukufumanisa ukusebenza kwesigcini.
Ngale nto, kunokuthiwa isangqa sebhakteriostatic esisebenzisa indlela yephepha enobubanzi obungaphezulu kwe-1.0mm sisebenza kakhulu. I-MIC ibizwa ngokuba yingxinano encinci yesigcini esinokongezwa kwindawo yokuthintela ukukhula kweentsholongwane. Kwimeko enjalo, i-MIC encinci, kokukhona iipropati ze-antimicrobial zesigcini esinokuqina.
Amandla okanye isiphumo somsebenzi we-antimicrobial sidla ngokubonakala ngendlela ye-minimum inhibitory concentration (MIC). Ngokwenza njalo, umsebenzi we-antimicrobial onamandla umiselwa lixabiso elincinci le-MIC. Nangona i-MIC ingenakusetyenziselwa ukwahlula phakathi komsebenzi we-bactericidal kunye ne-bacteriostatic, ii-surfactants zaziwa ngokubanzi ukuba zine-bacteriostatic effect kwi-concentration ephantsi kunye ne-sterilization effect kwi-concentration ephezulu.
Enyanisweni, ngamaxesha ahlukeneyo, ezi zinto zimbini zenzeka ngaxeshanye, kwaye oku kwenza kube nzima ukuzihlukanisa. Ngenxa yesi sizathu, zihlala zinikwa igama eliqokelelweyo njengokubulala iintsholongwane okanye ukubulala iintsholongwane.
Ixesha lokuthumela: Juni-10-2021