Ngaba i-phenoxyethanol iyingozi eluswini?

Yintoni iphenoxyethanol?
I-Phenoxyethanol yi-glycol ether eyenziwe ngokudibanisa amaqela e-phenolic kunye ne-ethanol, kwaye ibonakala njengeoli okanye i-mucilage kwimeko yayo yolwelo.Yinto eqhelekileyo egcina izinto zokuthambisa, kwaye inokufumaneka kuyo yonke into ukusuka kwiikhrimu zobuso ukuya kwiloshini.
I-Phenoxyethanol ifezekisa umphumo wayo wokulondoloza kungekhona nge-antioxidant kodwa ngomsebenzi wayo wokulwa ne-microbial, evimbela kwaye isuse iidosi ezinkulu zegram-positive kunye ne-negative microorganisms.Kwakhona kunempembelelo ebalulekileyo yokuthintela kwiintlobo zebhaktheriya eziqhelekileyo ezifana ne-E. coli kunye ne-Staphylococcus aureus.
Ngaba i-phenoxyethanol iyingozi eluswini?
I-Phenoxyethanol inokubulala xa ifakwe kwiidosi ezinkulu.Nangona kunjalo, ukusetyenziswa kwezihloko zephenoxyethanolekugxininiseni ngaphantsi kwe-1.0% isengaphakathi kuluhlu olukhuselekileyo.
Siye saxoxa ngaphambili ukuba i-ethanol i-metabolized kwi-acetaldehyde ngobuninzi obukhulu esikhumbeni kwaye ingaba ifunnwe ngobuninzi esikhumbeni.Zombini ezi zikwabaluleke kakhulu kwiphenoxyethanol.Kulusu olunomqobo ongaguqukiyo, i-phenoxyethanol yenye yezona zinto zikhawulezayo ukuthoba i-glycol ethers.Ukuba i-metabolism ye-phenoxyethanol ifana ne-ethanol, isinyathelo esilandelayo kukubunjwa kwe-acetaldehyde engazinzanga, ilandelwa yi-phenoxyacetic acid kunye nezinye ii-radicals zamahhala.
Sukuba nexhala okwangoku!Xa besixoxa nge-retinol ngaphambili, siphinde sakhankanya inkqubo ye-enzyme ehambelana nemetabolism yephenoxyethanol, kwaye ezi nkqubo zokuguqulwa zenzeka phantsi kwe-stratum corneum.Ke kufuneka sazi ukuba ingakanani na i-phenoxyethanol efunxekayo ngokwenyani.Kolunye uphononongo oluvavanye ukufunxwa kwe-sealant esekwe emanzini equlethe i-phenoxyethanol kunye nezinye izithako ezichasene ne-microbial, ulusu lwehagu (elona lunamandla okungena lula ebantwini) luya kutsala i-2% ye-phenoxyethanol, nayo yonyuka ukuya kwi-1.4% kuphela emva kweeyure ze-6. kunye ne-11.3% emva kweeyure ezingama-28.
Olu phononongo lucebisa ukuba ukufunxwa kunye nokuguqulwa kwephenoxyethanolekugxininiseni ngaphantsi kwe-1% ayiphezulu ngokwaneleyo ukuvelisa iidosi ezinobungozi ze-metabolites.Iziphumo ezifanayo nazo zifunyenwe kwizifundo kusetyenziswa iintsana ezisanda kuzalwa ngaphantsi kweeveki ezingama-27.Uphononongo lwathi, "Aqueousphenoxyethanolayibangeli umonakalo omkhulu wolusu xa kuthelekiswa ne-ethanol-based preservatives.I-Phenoxyethanol iyafunxwa eluswini lweentsana ezisandula ukuzalwa, kodwa ayiyenzi imveliso ye-oxidation phenoxyacetic acid ngezixa ezinkulu. yiphathe, woyika ntoni?
Ngubani na ongcono, phenoxyethanol okanye utywala?
Nangona i-phenoxyethanol yenziwe i-metabolized ngokukhawuleza kune-ethanol, i-concentration ephezulu ethintelweyo kwi-topical application ingaphantsi kakhulu kwi-1%, ngoko ayiluthelekiso olulungileyo.Ekubeni i-stratum corneum ithintela uninzi lweeamolekyu ukuba zifakwe, i-radicals yamahhala eyenziwa zezi zimbini zingaphantsi kakhulu kunezo ziveliswa yi-oxidation reactions yazo yonke imihla!Ngaphezu koko, ngenxa yokuba i-phenoxyethanol iqulethe amaqela e-phenolic ngendlela yeoli, iyaphuphuma kwaye yome kancinci.
Isishwankathelo
I-Phenoxyethanol sisilondolozi esiqhelekileyo esisetyenziswa kwizinto zokuthambisa.Ikhuselekile kwaye iyasebenza, kwaye yeyesibini kuphela kwiparabens ngokwemigaqo yokusetyenziswa.Nangona ndicinga ukuba i-parabens nayo ikhuselekile, ukuba ufuna iimveliso ngaphandle kweparabens, i-phenoxyethanol lukhetho oluhle!